$\binom{4}{3}\binom{6}{2} + \binom{4}{4}\binom{6}{1}$

$60 + 6 = 66$

$\binom{10}{5} - \binom{4}{0}\binom{6}{5} - \binom{4}{1}\binom{6}{4} - \binom{4}{2}\binom{6}{3}$

$80$